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Victor Arokia Doss, D.
- Anti-Lipidemic Effect of Alternanthera sessilis Linn in Diabetic Rats
Authors
1 Department of Biochemistry, PSG College of Arts and Science, Coimbatore- Pin 641014, Tamil Nadu, IN
2 Department Of Biochemistry, PSG College of Arts and Science, Coimbatore- Pin 641014, Tamil Nadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 2, No 2 (2010), Pagination: 169-170Abstract
Cardiovascular diseases are becoming an increasing problem worldwide. Hypercholesterolemia has been implicated as the major cause for Coronary Heart Diseases. Based on its high Flavonoid content of the herbal plant Althernanthera sessilis was tested for antihyperlipidemic property. It showed significant decreases in the levels of serum Total Cholesterol(TC), Triglyceride(TG), Low density lipoprotein(LDL), Very low density lipoprotein(VLDL) and significant increase in the level of High density lipoprotein(HDL) when administered orally for 28 days to alloxan induced hyperlipidemic rats at a dose of 150,300,450 mg/kg.- Antiulcer Activity of 50% Hydroethanolic Leaf Extract of Ruellia tuberosa l. and Dipteracanthus patulus (Jaca) On Pylorus Ligated Gastric Ulcer Model
Authors
1 Department of Biochemistry, PSG College of Arts and Science, Coimbatore, Tamil Nadu, IN
2 Department of Biochemistry, PSG College of Arts and Science, Coimbatore – 641014, Tamil Nadu, IN
Source
Research Journal of Pharmacognosy and Phytochemistry, Vol 1, No 3 (2009), Pagination: 198-200Abstract
The antiulcer activity of 50% hydroethanolic leaf extract of Ruellia tuberose L. and Dipteracanthus patulus (Jaca) was evaluated in rats against pylorus ligated gastric ulcer model. The plant extract were administered orally at a dose of 500mg/kg and famotidine at the dose of 20 mg/kg (standard drug). Ulcer index was common parameter studied in the ulcer model, further the gastric pH, total and free acidity, gastric volume and antioxidant leaves such as SOD, CAT, GSH and the effect on LPO and protein were analysed. Both the extracts produced significant reduction in ulcer index, along with increase in the antioxidant enzyme and protein leaves as compared to control group and the lipid peroxidation was reduced in the treated and drug administered groups. Thus the plant extracts possess, significant antiulcer as well as antioxidant property.
Keywords
Antiulcer, Antioxidant, Ulcer Index, Ruellia tuberose .L, Dipteracanthus patulus.- In Vitro Antioxidant Activity of Ethanolic Extract of Barleria cristata L. Leaves
Authors
1 Department of Biochemistry, PSG College of Arts and Science, Coimbatore, Tamil Nadu, IN